How Ketamine Therapy Is Changing the Game for OCD Treatment
It’s no secret that obsessive-compulsive disorder (OCD) can take over your day. Intrusive thoughts can appear out of nowhere, and the urge to carry out certain behaviors can feel overwhelming. Even when you know the thoughts don’t make sense, the cycle keeps repeating.
And when you’ve tried therapy, medications, or a combination of both, and you’re still stuck, it can feel like nothing is working. In fact, about half of the people with OCD experience significant impairment, which can make it feel as though nothing is changing.
That’s why more attention is turning to ketamine therapy. At Allied Psychiatry & Mental Health, Dr. Hadi Estakhri and his team offer ketamine as a different approach for people dealing with treatment-resistant OCD.
We offer both intravenous ketamine infusions and an intranasal spray in our Newport Beach, California, office. If you’re struggling with OCD, keep reading to learn how ketamine therapy is changing the game.
Why consider ketamine for OCD
There are a variety of reasons to consider ketamine for OCD, including:
It’s safe and has been used for decades
Ketamine has been used safely since 1964 as an anesthetic. More recently, it’s been utilized in the mental health space to help treat conditions like depression, post-traumatic stress disorder (PTSD), and OCD.
It can work fast
Unlike traditional medications, which can take 8-12 weeks to show results, ketamine often works much quicker, sometimes within hours to days.
It can reduce obsessive thoughts
Research has shown that ketamine may help reduce obsessive thoughts and compulsive behaviors, especially in people who haven’t responded to other treatments.
It can help both adults and teens with OCD
Research also suggests ketamine may provide rapid, short-term relief from OCD symptoms (even in teens) and is generally well tolerated, though ongoing treatment may be needed to maintain results.
How ketamine works for OCD
Ketamine works differently from standard medications. Instead of targeting serotonin, it acts on the NMDA receptors in your brain and increases glutamate, a chemical that helps with brain communication.
This leads to:
- Reduced intensity of intrusive thoughts
- Improved neural plasticity (your brain’s ability to form new patterns)
- Greater flexibility in how your brain responds to triggers
In other words, ketamine helps loosen the grip of obsessive thought patterns, which gives your brain a chance to reset and respond differently.
6 signs ketamine therapy might be right for you
Ketamine may be worth considering if you:
- Have tried multiple medications without enough relief
- Continue to experience intrusive thoughts or compulsions
- Feel stuck in repetitive mental or behavioral loops
- Struggle with anxiety tied to OCD
- Are looking for a faster-acting option
- Meet the medical criteria for ketamine therapy
For some people, ketamine helps create the mental space needed to engage more effectively in therapy.
What kind of results can you expect?
While results vary, many people notice fewer or less intense intrusive thoughts, reduced urge to perform compulsions, and improved mood and anxiety levels.
Ketamine isn’t a cure for OCD, but it can be a tool to help break the cycle enough for other treatments, like therapy, to work more effectively.
Getting started with ketamine therapy for OCD
Your first step is to schedule a consultation with Dr. Estakhri. During your appointment, he reviews your symptoms and health history to ensure you don’t have any contraindications.
If ketamine therapy is right for you, he’ll review your treatment options. We offer ketamine in two formats: as an intravenous infusion or as a nasal spray (Spravato®).
During treatment, you may experience:
- A sense of calm or detachment from intrusive thoughts
- Temporary changes in perception or awareness
- Mild side effects like nausea or dizziness
These effects are short-lived, but you’ll need someone to drive you home after your session.
Is ketamine therapy right for you?
If you’ve been feeling stuck or haven’t found relief with traditional approaches, this may be a new path forward.
Call Dr. Hadi Estakhri at 949-945-0927 or book an appointment online today to learn more about ketamine therapy for OCD.
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